Republican U.S. Senator Rob Portman, who recently rescinded his support for Donald Trump, and his Democratic challenger Ted Strickland are set to hold their first debate.
The candidates will square off on Friday in Youngstown.
The debate comes amid renewed attention to the Senate race after Portman pulled his endorsement of Trump following the release of a 2005 video, which captures the Republican presidential nominee making lewd comments about women.
Portman said he had hoped to support Trump out of respect for the millions of people who voted for him.